With reference to monoclonal antibodies, often mentioned in news, consider the following statements:
I. They are man-made proteins.
II. They stimulate immunological function due to their ability to bind to specific antigens.
III. They are used in treating viral infections like that of Nipah virus.
Which of the statements given above are correct?
Detailed Explanation:
Monoclonal antibodies (mAbs) are laboratory-made proteins designed to recognize and bind to a specific antigen.
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Statement I is Correct: They are man-made proteins produced in laboratories.
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Statement II is Correct: They bind to specific antigens and help the immune system identify or neutralize harmful pathogens.
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Statement III is Correct: Monoclonal antibodies are used in treating and preventing certain viral infections, including the Nipah virus.
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Therefore, all three statements are correct, making Option D the correct answer.
Statement-wise Analysis
| Statement | Status | Explanation |
|---|---|---|
| I. They are man-made proteins | ✅ Correct | Produced in laboratories from cloned immune cells. |
| II. They bind to specific antigens | ✅ Correct | Their high specificity helps target viruses, bacteria, or cancer cells. |
| III. Used against Nipah virus | ✅ Correct | Monoclonal antibodies have been developed and tested for Nipah virus treatment. |
Notes: Monoclonal Antibodies (mAbs)
What are Monoclonal Antibodies?
Monoclonal antibodies are identical laboratory-produced antibodies designed to target a specific antigen.
How do they work?
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Bind to a specific antigen.
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Block pathogens from infecting cells.
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Help the immune system destroy infected or abnormal cells.
Major Uses
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Cancer treatment
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Autoimmune diseases
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Viral infections (COVID-19, Ebola, Nipah)
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Diagnostic tests
Important Facts
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Developed using a single clone of immune cells, hence the term "monoclonal."
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They are highly specific compared to conventional drugs.
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Widely used in modern biotechnology and precision medicine.
Question 1 of 6 Vaccines and Immunization
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