In the context of vaccines manufactured to prevent COVID-19 pandemic, consider the following statements:
- The Serum Institute of India produced COVID-19 vaccine named Covishield using mRNA platform.
- Sputnik V vaccine is manufactured using vector-based platform.
- COVAXIN is an inactivated pathogen-based vaccine.
Which of the statements given above are correct?
Detailed Explanation:
Answer: Option 2 — 2 and 3 only
This question tests knowledge about different COVID-19 vaccine platforms used in India. Statement 1 is incorrect because Covishield is a viral vector vaccine (using chimpanzee adenovirus), not an mRNA vaccine. Statements 2 and 3 are correct as they accurately describe the platforms used for Sputnik V and COVAXIN respectively.
❌ Statement 1 – Incorrect: Covishield is a viral vector vaccine using chimpanzee adenovirus (ChAdOx1), not an mRNA platform vaccine.
✅ Statement 2 – Correct: Sputnik V uses a vector-based platform with two different human adenovirus vectors (rAd26 and rAd5) in a two-dose regimen.
✅ Statement 3 – Correct: COVAXIN, developed by Bharat Biotech, is an inactivated pathogen-based vaccine using the whole-virion inactivated Vero cell platform.
📝 Short Notes: COVID-19 Vaccine Platforms
| Vaccine Name | Manufacturer | Platform Type | Key Features |
|---|---|---|---|
| Covishield | Serum Institute of India (SII) | Viral Vector | Uses chimpanzee adenovirus (ChAdOx1) to deliver spike protein gene |
| Sputnik V | Gamaleya Institute (Russia) | Viral Vector | Uses two different human adenovirus vectors (rAd26 & rAd5) |
| COVAXIN | Bharat Biotech | Inactivated Pathogen | Whole-virion inactivated vaccine with adjuvant (Algel-IMDG) |
| Corbevax | Biological E | Protein Subunit | Uses receptor-binding domain (RBD) protein |
| Pfizer-BioNTech | Pfizer | mRNA | Uses mRNA to produce spike protein in cells |
| Moderna | Moderna | mRNA | mRNA-based platform similar to Pfizer |
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